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Articles from Dr. Knight and Dr. Di Giorgio on prevention, diagnostics, hormones, and heart health.
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Latest · November 6, 2026
Longevity Medicine Without the Hype: What the Science Actually Says About Living Better, Longer
Longevity medicine is having a moment. Some of it is fascinating, some of it may eventually change medicine, and some of it is getting far ahead of science. Here is what the evidence actually supports.
Dr. Jennifer KnightMD, FACP, MSCP, ABOIMEarlier Articles
31 articles, newest first.
- Longevity Medicine Without the Hype: What the Science Actually Says About Living Better, LongerLongevity medicine is having a moment. Some of it is fascinating, some of it may eventually change medicine, and some of it is getting far ahead of science.
- Your Body After 40: Why Is It Changing?Something feels different. Maybe you're not sleeping as well as you used to.
- How Early Does Artery Plaque Begin?A large study published in the New England Journal of Medicine in August 2026 imaged the arteries of 16,808 adults ages 18 to 70 in Denmark and Spain. None had known heart disease.
- Visceral Fat: Why Where You Carry Fat May Matter More Than What You WeighFor decades, we’ve been taught to think about weight as a number. Step on the scale. Calculate your BMI. Compare it with a chart.
- This Breast Cancer Awareness Month, Let’s Talk About PreventionEvery October, pink ribbons appear everywhere, and women are reminded to schedule their mammograms. That reminder matters.
- Why You’re Tired: Understanding Your Mitochondria and Cellular Energy” I hear some version of this constantly in my practice. Sometimes it’s waking up tired despite getting eight hours of sleep. m.
- On HRT and Still Tired? Let’s Talk About TestosteroneOne of the most frustrating things I hear from women in menopause sounds something like this: “My hot flashes are so much better. ” Maybe it’s brain fog.
- GLP-1 Medications Beyond Weight Loss: Could They Affect Longevity?A few years ago, most conversations about GLP-1 medications centered around diabetes and weight loss. That conversation has changed dramatically.
- VO₂ Max: The Fitness Metric That Helps Predict How Well You’ll AgeWhen most people think about cardiovascular health, they think about cholesterol, blood pressure, or plaque in their arteries. As a cardiologist, I care about all of those things.
- Microplastics and Heart Disease: What Patients Need to KnowMost of us don’t spend much time thinking about plastic. We recycle it. We drink from it. We store leftovers in it.
- Heart Disease in Women: How Do Menopause, Pregnancy, and Sex-Specific Differences Influence Cardiovascular Prevention?When most people think about heart disease, they picture an older man clutching his chest. For decades, that image shaped not only public perception, but much of cardiovascular research itself.
- The Menopause Symptoms No One Warns You AboutWhen most people think about menopause, they think about hot flashes. And yes, hot flashes are one of the most common symptoms.
- Does Everyone with High Cholesterol Need a Statin?If there’s one medication that seems to spark more debate than almost any other, it’s statins.
- Perimenopause: An Opportunity to Reclaim Your Health” They tell me they’re exhausted despite sleeping. Their anxiety feels different. They’re gaining weight even though they’re eating and exercising the same way they always have.
- Root-Cause Medicine: Treating the Why, Not Just the SymptomsOne of the things that surprises people most during their first visit with me is that we spend a lot of time talking about things that don’t seem related to the reason they came in.
- Functional Medicine vs Integrative Medicine: What’s the Difference?If you spend enough time searching for answers online, eventually you come across the term functional medicine. Most people are not really searching for a particular certification.
- When Does Perimenopause Start? Earlier Than You Think” You’re 39. Or 42. Or 44. You’re still getting periods. Sometimes they’re even perfectly regular. You aren’t having hot flashes, so hormones aren’t even on your radar.
- CVD Diagnostics and Advanced Screening ToolsDetecting Heart Disease Before It Starts Cardiovascular disease develops along a spectrum—beginning with common risk factors long before structural damage becomes apparent.
- CVD: Early Detection & PreventionCVD is the leading cause of death in women – including breast cancer survivors Up to 50% of heart attacks occur in people with no warning signs.
- Daily Nervous System Regulation: A Practical GuideBreathwork and mindfulness are powerful tools to help regulate your nervous system, improve mood, support hormonal balance, and reduce stress.
- Does REMS Echo Light replace DEXA ?” The answer is yes—you should still have your DEXA scan when it’s due, especially if it is covered by insurance.
- Homocysteine and Your HealthWhat is Homocysteine? Homocysteine is an amino acid in your blood related to a process called methylation, which helps your body function properly.
- Strong Bones, Strong Body: Why We Use DEXA, EchoLight, and InBody TogetherWhen most people think about their health, they focus on cholesterol numbers, blood pressure, or maybe the number on the scale.
- Adaptogens & Resilience: Boosting Well-Being in a Stressful WorldPlease note that the information here is for educational purposes only and is not a substitute for professional medical advice. Stress is an inevitable part of modern life—it’s everywhere.
- Cardiovascular Disease: It's Time to Rethink PreventionLet’s begin with a wake-up call. Cardiovascular disease (CVD) remains the leading cause of death worldwide—and it doesn’t discriminate.
- Genetics, Genomics, and Epigenetics: What’s the Difference?” Those are fair questions. For years, genetics was presented as destiny, something fixed and unchangeable.
- Homocysteine: One of the Most Overlooked (and Easily Fixable) Risk Factors for Heart Disease and DementiaAt Nova Wellness, we believe that some of the most powerful changes in health come from the simplest steps.
- How Hitting Rock Bottom at 40 Led Me to NAD+ and a New Path to HealthI entered my 30s feeling like I had it all: newly married to the woman of my dreams, a beautiful little girl, and another on the way.
- HRV: How I Learned to Listen to My BodyWhen I bought my first fitness watch several years ago, I assumed I’d just be tracking my runs and counting my steps. I never expected it to spark a transformation.
- Not All Supplements Are Created Equal: How to Choose the Ones That Truly WorkEvery week I’m asked where to buy supplements and which brands to trust. The reality is that the supplement industry is enormous, poorly regulated, and often misleading.
- The Galleri TestMost of us are familiar with routine cancer screenings such as mammograms, colonoscopies, and Pap smears. While these are important, they only screen for a small number of cancers.
- The EcholightEcholight is a radiation-free, advanced ultrasound technology that assesses both bone density and bone quality. It is fast, non-invasive, and performed in the office in just a few minutes.
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